The Villalta laboratory is directed towards understanding how immune cells contribute to tissue injury and repair in degenerative and autoimmune diseases.
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Research Interests: Sensory Neurobiology, Photoreceptor physiology, Visual cycle and dark adaptation, Photoreceptor degeneration, Gene-independent therapy for visual disorders
We are a sensory neurobiology lab interested in the function of mammalian rod and cone photoreceptors. Studies target…
Gene augmentation therapy for correcting mutations in the RPE65 gene is the first FDA-approved gene therapy for any genetically inherited disease. There is no doubt that further genetic editing represents a new frontier that will permit the…
Our research group is dedicated to understand the molecular basis of human diseases using structural biology, which allows us to visualize how proteins function or malfunction at the atomic level. A major area of our…
Our research seeks to understand how ion channels operate in health and illness. Ion channels are membrane proteins in all cells that catalyze the selective passage of ions across membranes and, like enzymes, show exquisite…
The long-term goal of our lab is to understand how mechanical forces modulate neural stem cell fate in development and repair at molecular, cellular and organismal levels. We previously showed that the stretch-activated ion channel…
My research is focused on identifying how experience modulates activity dynamics in neural circuits, both acutely and chronically. I aim to develop new methods and use these in combination with modern techniques such as optogenetics…
Research in Dr. Abbott’s lab is focused on elucidating the molecular basis for ion channel and transporter physiology and pathophysiology. One of the main directions of the lab is understanding the molecular basis for our…
The Ivy lab investigates neurobiological mechanisms of early-life aerobic exercise, and how they intersect with developmental plasticity of the brain. We specifically focus on exercise-induced epigenetic mechanisms involved in learning and memory.
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My lab studies the molecular sensors that allow cells to detect and respond to physical cues in their environment, including electrical and mechanical stimuli. Cells use these sensors to adapt to and modify their microenvironment,…