The Cognitive Neuroscience of Sleep lab (or CogNoS for short) uses neuroimaging, behavioral manipulations, and computational methods to explore memory reactivation during sleep, which broadly impacts cognition, emotion, and health. Exploring the mechanisms through which…
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Research Interests: Motivated behavior, Reward, Addiction and Substance Abuse, Dopamine, Decision Making…
The central mission of my laboratory is to develop new strategies to rejuvenate and protect the brain. Towards this end, we are pioneering inhibitory neuron transplantation approaches to discover principles for the reactivation of juvenile…
Amyloid, C1q, Alzheimer’s disease, apoptosis, successful aging, dementia
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Huntington’s disease (HD) is a devastating, inherited neurological disorder that causes psychiatric, cognitive and movement deficits.The Thompson laboratory is actively engaged in investigating the fundamental molecular and cellular events that underlie how the mutant HD…
Our lab uses multi-omic approaches to understand molecular mechanism of neurodegenerative diseases like Alzheimer’s disease and Fronto-temporal dementia (FTD). We use functional genomics approaches to better understand the role of distinct cell-types in disease pathophysiology…
The formation and expression of long-term memory (LTM) requires complex interplay between gene products, synapses, neurons, and distributed cellular networks. The long-term goals of my research program are to: (i) determine how gene expression activated…
In order to attain a natural reward like food, water, or sex, animals must know what and where rewards are, and how to get them. This is accomplished in part via the brain’s “reward circuitry,”…
Work in my laboratory is divided into three main research areas: 1) define the functional contributions of chemokines and chemokine receptors in defense and disease following viral infection of the central nervous system (CNS), 2)…
Intracellular calcium signaling; Alzheimer’s disease; autism spectrum disorder; immunoimaging; novel microscopies including multi-photon and lightsheet.
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