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1. Understanding oncogenic metabolic pathways in glioma stem cells (GSC) and their role in glioma progression and response to treatment. My laboratory has identified significant differences in protein processing and degradation in GSC, which…

Research objectives are to understand the mechanisms mediating addictive disorders. Special interest is on how gut, genes, brain, and behavior interact with environment (e.g., developmental drug exposure) to influence addiction. Focus is placed on gut…

Our research group is dedicated to understand the molecular basis of human diseases using structural biology, which allows us to visualize how proteins function or malfunction at the atomic level. A major area of our…

My lab studies the neurobiology and pharmacology of the endocannabinoids and other bioactive lipids. Our approach combines molecular and cellular biology, system biology and medicinal chemistry to discover transformative chemical probes that target lipid-signaling pathways….

Research in the Gall laboratory is focused on the cellular mechanisms of synaptic plasticity underlying learning and memory. Recent work has addressed the hypothesis that a form of synaptic plasticity thought to underlie memory, referred…

Our research seeks to understand how ion channels operate in health and illness. Ion channels are membrane proteins in all cells that catalyze the selective passage of ions across membranes and, like enzymes, show exquisite…

Founded by Fan-Gang Zeng in 2000, the Hearing and Speech (HESP) laboratory at UC Irvine has been conducting basic and translational research in the following areas. (1) Understand mechanisms underlying normal and pathological hearing, (2)…

My research focuses on robotics, wearable sensors, and computational neuroscience for movement rehabilitation focused on persons who have experienced a stroke. My group designs innovative rehabilitation technologies based on an understanding of neuromuscular control and…

Our research program focuses on neural circuit mechanisms that underlie sensory perception, learning and memory, and cognition. Using mouse models, we have made significant advances by showing cell-type specific and molecular signaling mechanisms underlying critical…

Our work is in basic and clinical vascular neurobiology, with a primary focus on mechanistic studies of stroke and cerebrovascular disease. We perform animal and cell culture studies, clinical investigations, and population studies.

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