The Marazzi Laboratory studies epigenetic and chromatin-mediated control of gene expression. We are interested in how mutations cause infection, inflammatory and neurodegenerative diseases. We use biochemistry, genetics, and next generation sequencing techniques to understand molecular mechanisms and genome-wide effects of known and novel candidate genes that cause juvenile forms of disease. We care about disease of young age. For reference, please see our recent works on neurodegeneration, inflammation and infection.